REMBRANDT INSTITUTE OF CARDIOVASCULAR SCIENCE

09:00-09:25

Registration with coffee / tea

09:25-09:30

Introduction & opening

Presenters: Prof. Paul Quax 

09:35-10:00

09:35-11:00

Plenary session (7 min presentation + 3 min discussion)

10:00-10:10

Michiel Blok -
Mesencephalic astrocyte-derived neurotrophic factor (MANF) is an expression marker for epicardium-derived cells post-myocardial infarction and modulates action potential firing activity in stellate ganglia neurons

10:10-10:20

Jeroen Molenaar -

Examining ApoB100 T-cell responses in atherosclerotic lesions by an adaptive transfer in vivo

10:20-10:30

Dionne Dubelaar -

Extracorporeal circulation-induced microcirculatory perfusion disturbances and edema are unaffected by pharmacological modulation of endothelial permeability using Tie2 activator razuprotafib

10:30-10:40

Artemiy Kovynev -

Timing matters: Late, but not early, exercise training ameliorates MASLD involving the gut-liver axis in mice

10:40-10:50

Jamilla Goedegebuur -

Clinical outcomes and use of antithrombotic therapy in patients with peripheral artery disease with incident venous thromboembolism: a Dutch nationwide cohort study

10:50-11:00

Eduard Pierre de Winter -

High-oxalate diet induced kidney failure affects arteriovenous fistula remodeling a murine model

11:00-11:30

Coffee / tea break 

11:30-12:30

Parallel session Room 1

(3 min presentation + 2 min discussion; room 1)

11:30–11:35

Noa Linthorst -

Targeted suppression of mutant von Willebrand factor using small interfering RNAs in in vitro models of von Willebrand disease type 2A

11:35-11:40

Maaike van Buuren -

The diurnal rhythm in the metabolic activity of brown adipose tissue coincides with diurnal excretion of mitochondrial proteins in extracellular vesicles

11:40-11:45

Lily Jalink -  

A novel protein might enhance cardiac cell communication in heart failure with preserved ejection fraction

11:45-11:50

Thijs Sluiter -

RhoGEF Trio-induced strengthening of the endothelial barrier regulates paracellular, but not transcellular migration of immune cells

11:50-11:55

Elisavet Koutala -

Development and characterization of hiPSC-derived blood vessel models for disease research.

11:55-12:00

Dejvid Veizaj -

In silico modeling of factor Xa – prothrombin complexes using AlphaFold-Multimer and Molecular Dynamics simulations for functional prediction

12:00-12:05

Jing Miao -

nhibition of NNMT reduces dyslipidemia to attenuate atherosclerosis development

12:05-12:10

Rudmer Postma -

Identification of pre-eclampsia subtypes by morphological profiling of endothelial cell responses to patient serum

12:10-12:15

Boudewijn Kruithof -

The influence of altered left ventricular-to-aortic flow angle on the aortic wall: an ex vivo flow model study

12:15-12:20

Jérémy Thalgott -

Non-invasive detection and functional characterization of pericyte dysfunction in hereditary hemorrhagic telangiectasia using super-resolution ultrasound - Identification of TGF-Beta as potential drug target

12:20-12:25

Ruben Methorst -

Anatomical dissection of pain perception in acute type A aortic dissection

12:25-12:30

Finn Timmermans -

Ultrafast doppler ultrasound for non-invasive assessment of microvascular dysfunction inside the body

12:30-12:35

Azra Husetic -

Employing human myocardial slices to study cardiac repair post-infarction

11:30-12:10

Parallel session room 2

(3 min presentation + 2 min discussion; room 2)

11:30–11:35

Emily Martens -

Incidence and determinants of venous thromboembolic and bleeding complications in patients with hepatocellular carcinoma – the Tityos study

11:35-11:40

Mohan Li -

Raising HDL protects against sepsis rather than cardiovascular disease

11:40-11:45

Esmeralda Meijboom -

Redirecting the wound healing after myocardial infarction towards cardiac regeneration by combining mechanical and pharmacological support.

11:45-11:50

Carolien Volleman -

Extracorporeal circulation-induced hemolysis is associated with endothelial dysfunction and acute kidney injury in a rat model

11:50-11:55

Lucie Delfos -

The mast cell – CD4+ T cell interplay in experimental atherosclerosis development

11:55-12:00

Anish Kanhai -

IgE+CD63+ mast cells positively associate with neovascularization in advanced human atherosclerosis

12:00-12:05

Clarissa Becher -

BMP9 attenuates IL-33 signaling and prevents from IL-33-induced endothelial-to-mesenchymal transition in Pulmonary Arterial Hypertension

12:05-12:10

Thomas Bos -

An interspecies comparison of autonomic innervation at the venous pole of the heart during human and mouse embryonic development

12:10-12:15

Xiaomeng Zhang -

he role of platelet glucose metabolism in microvascular complications of diabetes mellitus

12:15-12:20

Marius Wits -

Unraveling dysregulated BMP signaling in pulmonary arterial hypertension: Innovative NanoBRET approaches for early disease detection

12:20-12:25

Loukia Yiangou -

2D and 3D platforms for modelling cardiac fibrosis using hiPSC-derived cardiovascular cells

12:25-12:30

Elizaveta Polyakova -

Bio-engineering and recellularization of cardiac-derived extracellular matrix