Program 15th Rembrandt Symposium 2024 – www.rembrandtinstitute.nl

15th Rembrandt Symposium 01-11-2024

Annual meeting of the Rembrandt Institute for Cardiovascular Science (RICS)

1 November 2024, NH Conference Centre Leeuwenhorst, Noordwijkerhout

PROGRAM

09:00-09:25	Registration with coffee/tea
09:25-11:00	Plenary Session 1 Chairs: Charissa van den Brom & Patrick Rensen
09:25-09:30	Introduction & opening Presenters: Prof. Paul Quax & prof. Jaap van Buul
09:35-10:00	Keynote 1: Prof. Dr. Jeroen Eikenboom: Allele selective silencing of Von Willebrand factor
10:00-11:00	Oral plenary session Chairs: Charissa van den Brom & Patrick Rensen
10:00-10:10	Koen Prange - Human atherosclerotic plaque macrophages associate with clinical presentation and follow diverse lineage differentiation routes
10:10-10:20	Max Grönloh - Primary neutrophil adhesion triggers endothelial hotspots by increasing JNK1-MARCKSL1-mediated filopodia to promote secondary neutrophil transmigration.
10:20-10:30	Dagmar van Mourik - Autoantibodies of patients with antiphospholipid syndrome cross-react with gut commensal proteins
10:30-10:40	Wietse In het Panhuis - Inhibition of hepatic bile salt uptake by Myrcludex B attenuates atherosclerosis development in mice
10:40-10:50	Eduard de Winter - Intraoperative transit time flow measurement of radiocephalic arteriovenous fistulas predicts maturation
10:50-11:00	Lily Jalink - Unravelling the role of long non-coding RNA LINC00899 in heart failure with preserved ejection fraction
11:00-11:30	Coffee / tea break
11:30-12:45	Blitz Parallel Sessions

12:45-13:30	Lunch
13:30-14:00	PLENARY SESSION 2: Chairs: Stephan Huveneers & Erik Klok
13:30-14:00	Keynote 2: Prof. Dr. Ferdinand LeNoble (Karlsruhe, Germany): Molecular control of organo-typical angiogenesis
14:00-14:30	PLENARY SESSION 3: REMBRANDT PROJECT REPORTS 2019 Chairs: Reinier Boon & Jesper Hjortnaes
14:00-14:15	Rianne Schoon - VE-cadherin's novel binding proteins ARVCF and KEAP1 modulate the endothelial barrier in health and disease
14:15-14:30	Thijs Sluiter - Understanding and Targeting Intraplaque Angiogenesis to Reduce Vein Graft Atherosclerosis
14:30-15:00	Coffee/tea break
15:00-16:30	PLENARY SESSION 4: Chairs: Anke Smits & Marten Hoeksema
	Keynote Lecture 3: Jan Willem Buikema: Embryonic Signaling in Heart Failure: Ally or Enemy?

15:30-16:40	Oral parallel sessions Session 1: Atherosclerosis Oxford 18
15:30-15:40	Josephine Tan - PRDM16 suppresses synthetic smooth muscle cell phenotypic modulation in atherosclerosis
15:40-15:50	Viviana Meraviglia- Generation of isogenic allelic series of LMNAmutated hiPSC lines using the navel and highlyefficient targeting platform, STRAIGHT-IN
15:50-16:00	Emily Martens - The diagnostic performance of the YEARS and PEGeD algorithm in patients with prior venous thrombosis suspected of pulmonary embolism
16:00-16:10	Kayleigh van Dijk - Exploring PD-1 and Tissue Resident Memory T Cells in Atherosclerotic Diseases
16:10-16:20	Rocco Caliandro - Zeb2os-mediated ZEB2 inhibition in myocardial infarction-induced cardiac dysfunction
16:20-16:30	Milena Schönke - Exercise mimetic IC7Fc strongly reduces atherosclerosis by targeting lipoprotein metabolism and bile acid dynamics, surpassing statin efficacy

16:50-17:20	PLENARY SESSION 5: Awards
16:30-16:40	HeART in Science Awards Chair: Prof. Dr. Anton Jan van Zonneveld
16:40-16:45	Best Presentation Award & Prizes Presenters: organizing committee
16:45 -16:65	Rembrandt Grant 2023 Presenter: prof. Paul Quax
16:55-17:00	Closing remarks Presenters: prof. Paul Quax & prof. Jaap van Buul
17:00-18:00	Borrel & Drinks